Photodynamic therapy potential of Ruta chalepensis extracts: anticancer and photosensitizing effects

Ruta chalepensis extract (RCOE) exhibited significant ROS generation under photodynamic therapy, with PDT10 and PDT25 inducing 4-fold and 8-fold increases, respectively. This suggests its potential as a plant-based photosensitizer for PDT applications in cancer treatment.

Authors

Cennet Özay (ORCID: https://orcid.org/0000-0002-1120-6122)
Nermin Topaloğlu (ORCID: https://orcid.org/0000-0001-7001-8327)
Emel Bakay (ORCID: https://orcid.org/0000-0002-3042-810X)

Publication Details

Published: 2025-12-17
DOI: https://doi.org/10.1117/12.3097786
Primary Topic: Photodynamic Therapy Research Studies
Type: article
Field-Weighted Citation Impact: 0.00

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article

Photodynamic therapy potential of Ruta chalepensis extracts: anticancer and photosensitizing effects

Cennet Özay, Nermin Topaloğlu, Emel Bakay

Dec 17, 2025

Photodynamic Therapy Research Studies

article

Photodynamic therapy potential of Ruta chalepensis extracts: anticancer and photosensitizing effects

Cennet Özay, Nermin Topaloğlu, Emel Bakay

December 17, 2025article en

Abstract

Openalex Percentile: Top 41%

Photodynamic Therapy Research Studies

DOI Source OpenAlex

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Photodynamic therapy potential of Ruta chalepensis extracts: anticancer and photosensitizing effects — Cennet Özay, Nermin Topaloğlu, et al. · (2025) | TGRS Research Map | TGRS