Establishment of six human induced pluripotent stem cell lines from healthy Central Asian donors (IPBi115-A, IPBi116-A, IPBi117-A, IPBi119-A, IPBi124-A, and IPBi129-A)

Six human induced pluripotent stem cell (iPSC) lines (IPBi115-A, IPBi116-A, IPBi117-A, IPBi119-A, IPBi124-A, and IPBi129-A) were established from peripheral blood mononuclear cells (PBMCs) of healthy donors from Kazakhstan and Uzbekistan, representing Central Asian populations. These lines retained pluripotency, differentiated into the three germ layers, and showed normal karyotypes, with confirmed Sendai virus clearance, donor-matched STR profiles, and mycoplasma-free status. These iPSC resources expand population diversity for stem cell research and provide valuable platforms for disease modeling and drug screening, supporting human-based approaches in biomedical research.

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Publication Details

Journal
Stem Cell Research
Published
2025-12-17
DOI
https://doi.org/10.1016/j.scr.2025.103891
Primary Topic
Pluripotent Stem Cells Research
Type
article
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article

Establishment of six human induced pluripotent stem cell lines from healthy Central Asian donors (IPBi115-A, IPBi116-A, IPBi117-A, IPBi119-A, IPBi124-A, and IPBi129-A)

Jihwan Song, Yeul Hong Kim, Mahito Nakanishi, Chan Yeong Heo et al.
Stem Cell Research
Pluripotent Stem Cells Research
article

Establishment of six human induced pluripotent stem cell lines from healthy Central Asian donors (IPBi115-A, IPBi116-A, IPBi117-A, IPBi119-A, IPBi124-A, and IPBi129-A)

Jihwan Song, Yeul Hong Kim, Mahito Nakanishi, Chan Yeong Heo, Miju Lee, Seong‐Su Nah, Wungrak Choi, Mira Han
article en

Abstract

Six human induced pluripotent stem cell (iPSC) lines (IPBi115-A, IPBi116-A, IPBi117-A, IPBi119-A, IPBi124-A, and IPBi129-A) were established from peripheral blood mononuclear cells (PBMCs) of healthy donors from Kazakhstan and Uzbekistan, representing Central Asian populations. These lines retained pluripotency, differentiated into the three germ layers, and showed normal karyotypes, with confirmed Sendai virus clearance, donor-matched STR profiles, and mycoplasma-free status. These iPSC resources expand population diversity for stem cell research and provide valuable platforms for disease modeling and drug screening, supporting human-based approaches in biomedical research.

Stem Cell ResearchVol. 90
Institut Pasteur Korea (KR), University of Tsukuba (JP), Seoul National University Bundang Hospital (KR), CHA University (KR), NC bit (South Korea) (KR)
Openalex Percentile: Top 63%
Pluripotent Stem Cells Research
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Establishment of six human induced pluripotent stem cell lines from healthy Central Asian donors (IPBi115-A, IPBi116-A, IPBi117-A, IPBi119-A, IPBi124-A, and IPBi129-A) — Jihwan Song, Yeul Hong Kim, et al. · Stem Cell Research (2025) | TGRS Research Map | TGRS