Bilateral Ovarian Steroid Cell Tumor With One-Year Disease-Free Follow-Up: A Case Report

Ovarian steroid cell tumors are rare sex cord-stromal neoplasms that may produce androgens and present with nonspecific gynecologic symptoms. Bilateral involvement is particularly uncommon and raises important diagnostic and therapeutic challenges in young women. We describe the case of a 25-year-old woman with bilateral adnexal masses who was evaluated with cross-sectional imaging and surgery, leading to the diagnosis of an ovarian steroid cell tumor. Definitive management was planned in a multidisciplinary setting and included surgical resection, adjuvant systemic treatment, and structured clinical, biochemical, and radiologic surveillance. The patient has remained disease-free on follow-up. This case underscores the importance of considering steroid cell tumor in the differential diagnosis of solid ovarian masses in reproductive-age patients, the central role of histopathology and immunohistochemistry in confirming the diagnosis, and the need to balance oncologic safety with fertility and endocrine considerations in young women with rare ovarian tumors.

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Publication Details

Journal
Cureus
Published
2025-12-17
DOI
https://doi.org/10.7759/cureus.99466
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
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article

Bilateral Ovarian Steroid Cell Tumor With One-Year Disease-Free Follow-Up: A Case Report

Luis E. Muñoz, Luis Alejandro Barrera, Carlos E. Cardenas, Karla A Fabiani et al.
Cureus
Ovarian cancer diagnosis and treatment
article

Bilateral Ovarian Steroid Cell Tumor With One-Year Disease-Free Follow-Up: A Case Report

Luis E. Muñoz, Luis Alejandro Barrera, Carlos E. Cardenas, Karla A Fabiani, Guido Panchana
article en

Abstract

Ovarian steroid cell tumors are rare sex cord-stromal neoplasms that may produce androgens and present with nonspecific gynecologic symptoms. Bilateral involvement is particularly uncommon and raises important diagnostic and therapeutic challenges in young women. We describe the case of a 25-year-old woman with bilateral adnexal masses who was evaluated with cross-sectional imaging and surgery, leading to the diagnosis of an ovarian steroid cell tumor. Definitive management was planned in a multidisciplinary setting and included surgical resection, adjuvant systemic treatment, and structured clinical, biochemical, and radiologic surveillance. The patient has remained disease-free on follow-up. This case underscores the importance of considering steroid cell tumor in the differential diagnosis of solid ovarian masses in reproductive-age patients, the central role of histopathology and immunohistochemistry in confirming the diagnosis, and the need to balance oncologic safety with fertility and endocrine considerations in young women with rare ovarian tumors.

CureusVol. 17(12)
University of Guayaquil (EC), Universidad Espíritu Santo (EC), National Oncologic Institute (PA), Comisión Honoraria de Lucha contra el cáncer (UY), Hospital Metropolitano (EC)
Openalex Percentile: Top 48%
Ovarian cancer diagnosis and treatment
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