Downregulated MYL1 Emerges as a Promising Diagnostic Biomarker for Rheumatoid Arthritis

MYL1 is consistently downregulated in RA and may serve as a potential diagnostic biomarker. The results indicate that MYL1 may be involved in the pathological process of RA through calcium signaling, muscle function, and immune cell regulation. However, further clinical and mechanistic studies are warranted.

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Publication Details

Journal
Journal of Inflammation Research
Published
2025-12-01
DOI
https://doi.org/10.2147/jir.s551219
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
Field-Weighted Citation Impact
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article

Downregulated MYL1 Emerges as a Promising Diagnostic Biomarker for Rheumatoid Arthritis

William W. Lu, Yi Dan, Haidong Chen, Wenjun Hao et al.
Journal of Inflammation Research
Rheumatoid Arthritis Research and Therapies
article

Downregulated MYL1 Emerges as a Promising Diagnostic Biomarker for Rheumatoid Arthritis

William W. Lu, Yi Dan, Haidong Chen, Wenjun Hao, Can Yang, Wuxuan Qin, Xifan Zheng, Yan Chen, Yicheng Liang, Han Tang, Zhiling Huang
article en

Abstract

MYL1 is consistently downregulated in RA and may serve as a potential diagnostic biomarker. The results indicate that MYL1 may be involved in the pathological process of RA through calcium signaling, muscle function, and immune cell regulation. However, further clinical and mechanistic studies are warranted.

Journal of Inflammation ResearchVol. Volume 18
Guangxi Medical University (CN), Chinese University of Hong Kong (HK), First Affiliated Hospital of GuangXi Medical University (CN), Shenzhen Institutes of Advanced Technology (CN), University of Hong Kong (HK)
Openalex Percentile: Top 43%
Rheumatoid Arthritis Research and Therapies
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Downregulated MYL1 Emerges as a Promising Diagnostic Biomarker for Rheumatoid Arthritis — William W. Lu, Yi Dan, et al. · Journal of Inflammation Research (2025) | TGRS Research Map | TGRS