Synthesis of <i>N</i> -trifluoromethylthio-1 <i>H</i> -isochromen-1-imines <i>via N</i> -trifluoromethylthiolation/iminolactonization of <i>o</i> -alkynyl aryl amides with <i>N</i> -trifluoromethylthiosaccharin
A simple and practical synthetic method for the construction of N -trifluoromethylthio-1 H -isochromen-1-imines from o -alkynyl aryl primary amides using N -trifluoromethylthiolation/iminolactonization was developed.
Authors
- Changge Zheng (ORCID: https://orcid.org/0000-0001-7047-1594)
- Qiang Wang (ORCID: https://orcid.org/0000-0003-1935-2631)
- Dejing Yin
- Xiaoyu Wang (ORCID: https://orcid.org/0000-0002-2139-3152)
- Jie Wang (ORCID: https://orcid.org/0000-0002-7512-4572)
- Wenqi Li (ORCID: https://orcid.org/0000-0003-3979-6379)
- Feng Zheng
- Xiaoxu Liu (ORCID: https://orcid.org/0000-0002-8705-2000)
- Peng Cao (ORCID: https://orcid.org/0000-0001-8199-0015)
- Jianquan Hong (ORCID: https://orcid.org/0000-0001-9212-6425)
Institutions
- Jiangnan University (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1039/d5qo01223f
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00