Innovative minicircle DNA vector encoding pri-miR-375 silences E6 and E7 oncoproteins in HPV16-positive CaSki cells
These results suggest that mcDNA-pri-miR-375 vector has the potential to be further explored in gene therapy for the treatment of HPV-caused cervical cancer.
Authors
- João A. Queiroz (ORCID: https://orcid.org/0000-0002-3096-8325)
- Fani Sousa (ORCID: https://orcid.org/0000-0001-9996-2194)
- Joana F. A. Valente (ORCID: https://orcid.org/0000-0002-2408-9762)
- A.M. Almeida (ORCID: https://orcid.org/0000-0002-9313-6649)
- Diego Pereira (ORCID: https://orcid.org/0000-0002-2612-4672)
- Ângela Sousa (ORCID: https://orcid.org/0000-0001-9155-7581)
Institutions
- University of Beira Interior (PT)
- Instituto Politécnico de Leiria (PT)
Publication Details
- Journal
- Gene
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1016/j.gene.2025.149964
- Citations
- 1
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.81