Valacyclovir Treatment of Early Symptomatic Alzheimer Disease

This trial aimed to assess whether valacyclovir, an antiviral medication targeting herpes simplex virus, could improve cognitive outcomes in patients with early symptomatic Alzheimer disease who had seropositivity for herpes simplex virus.

Publication Details

Journal
JAMA
Published
2025-12-17
DOI
https://doi.org/10.1001/jama.2025.22830
Primary Topic
Herpesvirus Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
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article

Valacyclovir Treatment of Early Symptomatic Alzheimer Disease

JAMA
Herpesvirus Infections and Treatments
article

Valacyclovir Treatment of Early Symptomatic Alzheimer Disease

article en

Abstract

This trial aimed to assess whether valacyclovir, an antiviral medication targeting herpes simplex virus, could improve cognitive outcomes in patients with early symptomatic Alzheimer disease who had seropositivity for herpes simplex virus.

JAMAVol. 335(6)
Openalex Percentile: Top 48%
Herpesvirus Infections and Treatments
DOISourceOpenAlex
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Valacyclovir Treatment of Early Symptomatic Alzheimer Disease · JAMA (2025) | TGRS Research Map | TGRS