Endocrine Adaptations to Prolonged Fasting: From Physiology, Clinical Uncertainties, Translational Challenges to Healthspan Implications

Overall, prolonged fasting activates conserved endocrine mechanisms that may confer plausible cardiometabolic benefits; however, their translation to clinical practice remains speculative. We highlight key knowledge gaps and propose directions for future research in this emerging field.

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Publication Details

Journal
Nutrients
Published
2025-12-17
DOI
https://doi.org/10.3390/nu17243949
Primary Topic
Dietary Effects on Health
Type
article
Field-Weighted Citation Impact
0.00

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article

Endocrine Adaptations to Prolonged Fasting: From Physiology, Clinical Uncertainties, Translational Challenges to Healthspan Implications

Andrej Janež, Luka Lipar, Jure Tršan, Rok Herman et al.
Nutrients
Dietary Effects on Health
article

Endocrine Adaptations to Prolonged Fasting: From Physiology, Clinical Uncertainties, Translational Challenges to Healthspan Implications

Andrej Janež, Luka Lipar, Jure Tršan, Rok Herman, Mojca Jensterle
article en

Abstract

Overall, prolonged fasting activates conserved endocrine mechanisms that may confer plausible cardiometabolic benefits; however, their translation to clinical practice remains speculative. We highlight key knowledge gaps and propose directions for future research in this emerging field.

NutrientsVol. 17(24)
University of Ljubljana (SI), Ljubljana University Medical Centre (SI)
Javna Agencija za Raziskovalno Dejavnost RS
Openalex Percentile: Top 50%
Dietary Effects on Health
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