Baicalin affects the progression of diabetic retinopathy through the RAGE/PXDN/PI3K/AKT pathway
This study revealed that BAI regulates the progression of DR by regulating the RAGE/PXDN (FN1)/PI3K/AKT signalling pathway. These findings not only provide new molecular insights into the pathogenesis of DR but also lay an important theoretical foundation for the development of new therapeutic strategies.
Authors
- Huirui Liu
- Jun Yang (ORCID: https://orcid.org/0000-0002-7460-2800)
- Jianwen Wang (ORCID: https://orcid.org/0000-0001-7824-4193)
- Yi Gao
Institutions
- Harbin Medical University (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
- Heilongjiang University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1186/s12967-025-07590-0
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 0.00