Age-Dependent Muscular Response to Testosterone-Based Gender-Affirming Therapy: Evidence From a 1-Year Observational Study
Age at GAHT initiation markedly influences the anabolic response to testosterone therapy. Strength gains are more pronounced in early adulthood and decline with age, information that may assist clinicians in providing age-appropriate counseling for individuals beginning testosterone therapy.
Authors
- Gloria Beraldo (ORCID: https://orcid.org/0000-0001-8937-9739)
- Marinel Mór Dall’Agnol (ORCID: https://orcid.org/0000-0001-5783-7061)
- Alberto Ferlin (ORCID: https://orcid.org/0000-0001-5817-8141)
- Caterina Gregorio (ORCID: https://orcid.org/0000-0002-8163-1634)
- Andrea Garolla (ORCID: https://orcid.org/0000-0003-4736-9051)
- Giuseppe Sergi (ORCID: https://orcid.org/0000-0001-9757-856X)
- Alberto Scala (ORCID: https://orcid.org/0009-0009-1960-537X)
- Sandro Savino (ORCID: https://orcid.org/0000-0003-0184-7580)
- Giulia Termini (ORCID: https://orcid.org/0000-0001-8544-8274)
- Chiara Ceolin (ORCID: https://orcid.org/0000-0001-5064-1672)
- Davide Liborio Vetrano (ORCID: https://orcid.org/0000-0002-3099-4830)
- Marina De Rui (ORCID: https://orcid.org/0000-0003-4966-1312)
Institutions
- University of Padua (IT)
- Stockholm University (SE)
- Karolinska Institutet (SE)
- Stockholm Gerontology Research Center Foundation (SE)
- National Research Council (IT)
- Institute of Cognitive Sciences and Technologies (IT)
Publication Details
- Journal
- Endocrine Practice
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.eprac.2025.12.012
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00