Analysis of age-specific adverse events with vancomycin: a real-world pharmacovigilance study based on the FAERS database

Real-world data from the large-scale FAERS database were used to detect vancomycin-associated adverse event signals by disproportionality analysis, Age-stratified comparisons revealed marked differences in adverse event signal. This pharmacovigilance research underscored potential safety concerns of vancomycin, corroborated known risks and identified novel safety signals not listed in the current product label. These findings expanded understanding of vancomycin's safety profile and provided evidence-based guidance for clinical practice.

Authors

Institutions

Publication Details

Journal
International Journal of Surgery
Published
2025-12-17
DOI
https://doi.org/10.1097/js9.0000000000004563
Primary Topic
Pharmacovigilance and Adverse Drug Reactions
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Analysis of age-specific adverse events with vancomycin: a real-world pharmacovigilance study based on the FAERS database

Xiang Liu, Tingting Zhang, Chen Wang, Pei Guo et al.
International Journal of Surgery
Pharmacovigilance and Adverse Drug Reactions
article

Analysis of age-specific adverse events with vancomycin: a real-world pharmacovigilance study based on the FAERS database

Xiang Liu, Tingting Zhang, Chen Wang, Pei Guo, Zujun Wen, Peng Liu
article en

Abstract

Real-world data from the large-scale FAERS database were used to detect vancomycin-associated adverse event signals by disproportionality analysis, Age-stratified comparisons revealed marked differences in adverse event signal. This pharmacovigilance research underscored potential safety concerns of vancomycin, corroborated known risks and identified novel safety signals not listed in the current product label. These findings expanded understanding of vancomycin's safety profile and provided evidence-based guidance for clinical practice.

International Journal of Surgery
Xiyuan Hospital (CN), The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Dazhou Central Hospital (CN), Chongqing Medical and Pharmaceutical College (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 58%
Pharmacovigilance and Adverse Drug Reactions
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.