Thoraco‐Omphalopagus Conjoined Twins Following <scp>IVF</scp> With Day 5 Embryo Transfer: A Rare Case Report and Multidisciplinary Management Approach

Conjoined twinning is a rare and severe complication of monozygotic pregnancies. Assisted reproductive technologies (ART), including in vitro fertilization (IVF), may increase the risk of such anomalies. We report a case of thoraco-omphalopagus conjoined twins following a day 5 embryo transfer after IVF with intracytoplasmic sperm injection (ICSI). The diagnosis was made by ultrasound at 8 weeks' gestation and confirmed the presence of fused thoracic and abdominal structures with a shared heart. The pregnancy was managed through multidisciplinary counseling, and termination was performed following spontaneous fetal demise. This case underscores the importance of early imaging, detailed embryologic understanding, and coordinated care in managing rare IVF-associated anomalies.

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Publication Details

Journal
Clinical Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1002/ccr3.71288
Primary Topic
Assisted Reproductive Technology and Twin Pregnancy
Type
article
Field-Weighted Citation Impact
0.00

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article

Thoraco‐Omphalopagus Conjoined Twins Following IVF With Day 5 Embryo Transfer: A Rare Case Report and Multidisciplinary Management Approach

Rodrigo Ruano, Natalia Ravelo, George R. Attia, Patryk Piekos
Clinical Case Reports
Assisted Reproductive Technology and Twin Pregnancy
article

Thoraco‐Omphalopagus Conjoined Twins Following IVF With Day 5 Embryo Transfer: A Rare Case Report and Multidisciplinary Management Approach

Rodrigo Ruano, Natalia Ravelo, George R. Attia, Patryk Piekos
article en

Abstract

Conjoined twinning is a rare and severe complication of monozygotic pregnancies. Assisted reproductive technologies (ART), including in vitro fertilization (IVF), may increase the risk of such anomalies. We report a case of thoraco-omphalopagus conjoined twins following a day 5 embryo transfer after IVF with intracytoplasmic sperm injection (ICSI). The diagnosis was made by ultrasound at 8 weeks' gestation and confirmed the presence of fused thoracic and abdominal structures with a shared heart. The pregnancy was managed through multidisciplinary counseling, and termination was performed following spontaneous fetal demise. This case underscores the importance of early imaging, detailed embryologic understanding, and coordinated care in managing rare IVF-associated anomalies.

Clinical Case ReportsVol. 13(12)
University of Miami (US)
University of Miami
Openalex Percentile: Top 50%
Assisted Reproductive Technology and Twin Pregnancy
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