Thoraco‐Omphalopagus Conjoined Twins Following <scp>IVF</scp> With Day 5 Embryo Transfer: A Rare Case Report and Multidisciplinary Management Approach
Conjoined twinning is a rare and severe complication of monozygotic pregnancies. Assisted reproductive technologies (ART), including in vitro fertilization (IVF), may increase the risk of such anomalies. We report a case of thoraco-omphalopagus conjoined twins following a day 5 embryo transfer after IVF with intracytoplasmic sperm injection (ICSI). The diagnosis was made by ultrasound at 8 weeks' gestation and confirmed the presence of fused thoracic and abdominal structures with a shared heart. The pregnancy was managed through multidisciplinary counseling, and termination was performed following spontaneous fetal demise. This case underscores the importance of early imaging, detailed embryologic understanding, and coordinated care in managing rare IVF-associated anomalies.
Authors
- Rodrigo Ruano (ORCID: https://orcid.org/0000-0002-3642-5858)
- Natalia Ravelo
- George R. Attia
- Patryk Piekos (ORCID: https://orcid.org/0000-0002-5534-4172)
Institutions
- University of Miami (US)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/ccr3.71288
- Primary Topic
- Assisted Reproductive Technology and Twin Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Miami