ESAT-6 Modulates Macrophage Apoptosis in Mycobacterium Tuberculosis via lncNEAT1/miR-125b-5p/TNF-α Pathway
The results of this study indicated that ESAT-6 induces macrophage apoptosis by regulating lncNEAT1/miR-125b-5p/TNF-α pathway, which may provide a possible therapeutic target for the treatment of TB.
Authors
- Ayiguli Alimu
- Zulipikaer Abudureheman (ORCID: https://orcid.org/0000-0002-2122-0008)
- Aifang Zheng
- Li Li (ORCID: https://orcid.org/0000-0002-8711-9156)
- Hui Gong (ORCID: https://orcid.org/0000-0002-7833-433X)
- Jingran Xu (ORCID: https://orcid.org/0000-0002-8182-3927)
- Tuerhongjiang Axirejiang
- Abudushalamu Abuduwake
- Meiheriban Mamuti
Institutions
- People's Hospital of Kaizhou District (CN)
- Qujiang People's Hospital (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/idr.s560253
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Xinjiang