<i>Neisseria meningitidis</i> bacteraemia and lobar pneumonia in a previously healthy, fully immunised (including meningococcal vaccines) Irish teenager

An adolescent female patient presented to the Emergency Department of a large tertiary hospital in Ireland, with a 1-day history of chest and left axillary pain, and a 5-day history of productive cough, fever, reduced oral intake and lethargy; no previous medical history, sick contacts or recent travel. Vaccinations were up to date. Symptomatology, raised inflammatory markers, radiographic findings, coupled with relevant auscultatory findings, led to a diagnosis of community-acquired pneumonia. Less than 24 hours after presentation, <i>Neisseria meningitidis</i> was isolated from a blood culture, prompting patient isolation and commencement of high-dose ceftriaxone. Close contacts received prophylaxis, and public health authorities were notified. Meningococcal pneumonia, although infrequently seen in adults, has been reported in the paediatric population to date only rarely. This case serves as a reminder that meningococcal disease is notifiable, requiring prompt reporting to public health authorities, patient isolation and prophylaxis for close contacts. It also highlights meningococcal pneumonia as a cause of paediatric pneumonia, even in fully vaccinated, immunocompetent children, and the importance of obtaining blood samples for culture before commencing antibiotic therapy to maximise microbiological confirmation.

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Publication Details

Journal
BMJ Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1136/bcr-2025-268263
Primary Topic
Bacterial Infections and Vaccines
Type
article
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article

Neisseria meningitidis bacteraemia and lobar pneumonia in a previously healthy, fully immunised (including meningococcal vaccines) Irish teenager

Edina Moylett, Simon F. Lacey
BMJ Case Reports
Bacterial Infections and Vaccines
article

Neisseria meningitidis bacteraemia and lobar pneumonia in a previously healthy, fully immunised (including meningococcal vaccines) Irish teenager

Edina Moylett, Simon F. Lacey
article en

Abstract

An adolescent female patient presented to the Emergency Department of a large tertiary hospital in Ireland, with a 1-day history of chest and left axillary pain, and a 5-day history of productive cough, fever, reduced oral intake and lethargy; no previous medical history, sick contacts or recent travel. Vaccinations were up to date. Symptomatology, raised inflammatory markers, radiographic findings, coupled with relevant auscultatory findings, led to a diagnosis of community-acquired pneumonia. Less than 24 hours after presentation, <i>Neisseria meningitidis</i> was isolated from a blood culture, prompting patient isolation and commencement of high-dose ceftriaxone. Close contacts received prophylaxis, and public health authorities were notified. Meningococcal pneumonia, although infrequently seen in adults, has been reported in the paediatric population to date only rarely. This case serves as a reminder that meningococcal disease is notifiable, requiring prompt reporting to public health authorities, patient isolation and prophylaxis for close contacts. It also highlights meningococcal pneumonia as a cause of paediatric pneumonia, even in fully vaccinated, immunocompetent children, and the importance of obtaining blood samples for culture before commencing antibiotic therapy to maximise microbiological confirmation.

BMJ Case ReportsVol. 18(12)
Ollscoil na Gaillimhe – University of Galway (IE), University Hospital Galway (IE)
Openalex Percentile: Top 61%
Bacterial Infections and Vaccines
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