The Value of Oligoclonal Bands in Multiple Sclerosis Compared to Other Neurological Disorders: A Retrospective Data Analysis From an Austrian Tertiary Center
CSF-specific OCB have a high sensitivity and specificity and a very high NPV for diagnosing MS. However, the PPV was lower in this cohort. These findings must be carefully considered when diagnosing MS and interpreting OCB, especially in the context of differential diagnostic workup.
Authors
- Tobias Monschein (ORCID: https://orcid.org/0000-0002-6053-4210)
- Thomas Perkmann (ORCID: https://orcid.org/0000-0002-7976-0285)
- Barbara Kornek (ORCID: https://orcid.org/0000-0002-1851-6967)
- Paulus Stefan Rommer (ORCID: https://orcid.org/0000-0001-5209-6647)
- Gabriel Bsteh (ORCID: https://orcid.org/0000-0002-0825-0851)
- Markus Ponleitner (ORCID: https://orcid.org/0000-0002-3709-1845)
- Nik Krajnc (ORCID: https://orcid.org/0000-0002-4146-5870)
- Thomas Berger (ORCID: https://orcid.org/0000-0001-5626-1144)
- Fritz Leutmezer (ORCID: https://orcid.org/0000-0001-5665-8635)
- Tobias Zrzavy (ORCID: https://orcid.org/0000-0001-8909-1591)
- Fabian Föttinger (ORCID: https://orcid.org/0009-0005-7970-5349)
- Benjamin Scheicher
Institutions
- Medical University of Vienna (AT)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1111/ene.70471
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00