Neuroprotective Effects of Tuina in CP Rats Are Associated With Gut Microbiota Remodeling and Intestinal Barrier Restoration
Tuina significantly alleviated brain injury and improved motor function in CP rats. These effects were associated with modulation of the gut microbiota and restoration of intestinal barrier integrity, suggesting that the gut-brain axis may mediate the neuroprotective effects of Tuina.
Authors
- Lijian Xie (ORCID: https://orcid.org/0000-0002-0328-6820)
- Chenqin Si (ORCID: https://orcid.org/0000-0002-3036-0440)
- Danmei Chen (ORCID: https://orcid.org/0000-0002-7065-9922)
- Ayipaxiaguli Kasimu (ORCID: https://orcid.org/0000-0001-9382-3011)
- Yu Liu (ORCID: https://orcid.org/0009-0007-3205-1557)
- Bing Li (ORCID: https://orcid.org/0000-0001-5709-9396)
- Rui Qiao (ORCID: https://orcid.org/0000-0001-6225-9913)
- Pingping Sun (ORCID: https://orcid.org/0000-0002-8446-5598)
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Jinshan Hospital of Fudan University (CN)
- Yunnan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/brb3.71136
- Citations
- 1
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.81
Funders
- National Natural Science Foundation of China