Unsaturated Fatty Acid Metabolic Reprogramming in Psoriatic Skin Drives Inflammation and Predicts Response to Biologic Therapy
Our findings elucidate the pathway-level metabolic basis of psoriasis inflammation and provide a clinically applicable tool for predicting response to biologic therapy. The results highlight the importance of UFA metabolic reprogramming in psoriatic pathogenesis and offer new avenues for treatment personalization.
Authors
- Lixin Wang
- Liangliang Li (ORCID: https://orcid.org/0000-0003-4185-3109)
- Haijun Miao (ORCID: https://orcid.org/0009-0009-0477-0567)
- Yang Luo
- Xiao Ting Guan
Institutions
- 82th Hospital of Pla (CN)
Publication Details
- Journal
- Clinical Cosmetic and Investigational Dermatology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/ccid.s569278
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00