ADC for SCLC Clears Phase I

ZL-1310, an antibody-drug conjugate that targets DLL3-expressing small cell lung cancer cells, led to responses in nearly half of patients in a phase I study. These results provide further evidence that targeting DLL3 may be a promising approach for treating this cancer.

Publication Details

Journal
Cancer Discovery
Published
2025-12-05
DOI
https://doi.org/10.1158/2159-8290.cd-nw2025-0107
Primary Topic
Lung Cancer Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

ADC for SCLC Clears Phase I

Cancer Discovery
Lung Cancer Research Studies
article

ADC for SCLC Clears Phase I

article en

Abstract

ZL-1310, an antibody-drug conjugate that targets DLL3-expressing small cell lung cancer cells, led to responses in nearly half of patients in a phase I study. These results provide further evidence that targeting DLL3 may be a promising approach for treating this cancer.

Cancer DiscoveryVol. 16(1)
Openalex Percentile: Top 44%
Lung Cancer Research Studies
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ADC for SCLC Clears Phase I · Cancer Discovery (2025) | TGRS Research Map | TGRS