Somatic Mutations of Thymic Epithelial Tumors Identified in the Prospective <scp>THYMOGENE</scp> Trial
GTF2I mutations drive the growth of a significant portion of thymic epithelial tumors, often in conjunction with other gene mutations. Somatic mutations are not commonly found in many GTF2I wild-type tumors, where the underlying genomic abnormalities remain elusive, even when using a dedicated tool for sequencing thymic epithelial tumors.
Authors
- Marco Lucchi (ORCID: https://orcid.org/0000-0001-9909-6820)
- Serena Barachini (ORCID: https://orcid.org/0000-0002-4972-7927)
- Iacopo Petrini (ORCID: https://orcid.org/0000-0002-7752-6866)
- Franca Melfi (ORCID: https://orcid.org/0000-0002-1773-8269)
- Fabio Coppedè (ORCID: https://orcid.org/0000-0002-3081-6647)
- Irene Sofia Burzi (ORCID: https://orcid.org/0000-0001-9359-6533)
- Eleonora Pardini (ORCID: https://orcid.org/0000-0003-1285-601X)
- Diana Bacchin (ORCID: https://orcid.org/0000-0002-5706-0974)
- Melania Guida (ORCID: https://orcid.org/0000-0003-1968-5874)
- Michelangelo Maestri (ORCID: https://orcid.org/0000-0003-0960-4938)
- Vittorio Aprile (ORCID: https://orcid.org/0000-0001-8538-1719)
- Vanessa Nicolì (ORCID: https://orcid.org/0000-0003-2751-7352)
- Federico Cucchiara (ORCID: https://orcid.org/0000-0002-0946-750X)
- Marina Montali (ORCID: https://orcid.org/0000-0001-8804-4320)
- Gisella Sardo Infirri (ORCID: https://orcid.org/0009-0001-1227-9139)
- Roberta Ricciardi (ORCID: https://orcid.org/0009-0006-9506-0904)
- Carmelina Cristina Zafira
Institutions
- University of Pisa (IT)
- University of Rome Tor Vergata (IT)
Publication Details
- Journal
- Thoracic Cancer
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1111/1759-7714.70205
- Citations
- 1
- Primary Topic
- Myasthenia Gravis and Thymoma
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Regione Toscana