Shared donor–recipient γδ T‐cell phenotypic and repertoire features associate with cytomegalovirus reactivation after allogeneic haematopoietic stem cell transplantation
Overall, Vδ1+ and Vδ2+ T-cell phenotypic profiles and γδ TCR repertoire remain stable post-HSCT. This stability is disrupted by CMV reactivation, which is potentially associated with γδ+ T-cells of donor origin and γδ TCR repertoire.
Authors
- Martin Solders (ORCID: https://orcid.org/0000-0001-6951-1958)
- Johan Törlén (ORCID: https://orcid.org/0000-0002-3039-5133)
- Ahmed Gaballa (ORCID: https://orcid.org/0000-0002-5277-5129)
- Arwen Stikvoort (ORCID: https://orcid.org/0000-0002-0251-5628)
- Lucas C. M. Arruda (ORCID: https://orcid.org/0000-0002-8573-9618)
- Faisal Alagrafi (ORCID: https://orcid.org/0009-0008-4812-0729)
- Sofie Vonlanthen (ORCID: https://orcid.org/0000-0002-6215-7631)
- Paula Hahn (ORCID: https://orcid.org/0000-0003-4246-6821)
- Michael Uhlin (ORCID: https://orcid.org/0000-0002-2177-6727)
- Thomas Poiret (ORCID: https://orcid.org/0000-0003-1965-3522)
Institutions
- King Abdulaziz City for Science and Technology (SA)
- Karolinska University Hospital (SE)
- Karolinska Institutet (SE)
- Integrated Cardio Metabolic Centre (SE)
Publication Details
- Journal
- Clinical & Translational Immunology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/cti2.70068
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cancerfonden
- Stockholms Läns Landsting
- Vetenskapsrådet
- King Abdulaziz City for Science and Technology
- Barncancerfonden