Sodium-glucose transporters SGLT1 and SGLT2 in equine renal, hepatic and pancreatic tissue

The present study confirms presence of SGLT2 and SGLT1 in the equine kidney, localized to the proximal tubule. Also, presence of SGLT2 in the liver and pancreas, suggest that SGLT2i may have both renal and extrarenal effects.

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Publication Details

Journal
BMC Veterinary Research
Published
2025-12-17
DOI
https://doi.org/10.1186/s12917-025-05173-1
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Sodium-glucose transporters SGLT1 and SGLT2 in equine renal, hepatic and pancreatic tissue

Cathrine T. Fjordbakk, Runa Rørtveit, Carl Ekstrand, Camilla Anger-Håål et al.
BMC Veterinary Research
Diabetes Treatment and Management
article

Sodium-glucose transporters SGLT1 and SGLT2 in equine renal, hepatic and pancreatic tissue

Cathrine T. Fjordbakk, Runa Rørtveit, Carl Ekstrand, Camilla Anger-Håål, Fredrik S. Skedsmo
article en

Abstract

The present study confirms presence of SGLT2 and SGLT1 in the equine kidney, localized to the proximal tubule. Also, presence of SGLT2 in the liver and pancreas, suggest that SGLT2i may have both renal and extrarenal effects.

BMC Veterinary ResearchVol. 22(1)
Swedish University of Agricultural Sciences (SE), Norwegian University of Life Sciences (NO)
Openalex Percentile: Top 47%
Diabetes Treatment and Management
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