Performance of GPT‐5 in the Interpretation of IBD Histopathology Reports
GPT-5 demonstrated reliable performance in interpreting IBD histological reports, exhibiting high accuracy and strong agreement with the reference standard. While unreliable for IBD-U, GPT-5 may serve as a supportive tool in histopathological interpretation of IBD, particularly in centers with limited access to expert pathologists or IBD-specialists.
Authors
- Antonio Rispo (ORCID: https://orcid.org/0000-0002-1454-2412)
- Ambrogio Orlando (ORCID: https://orcid.org/0000-0002-5298-2638)
- Antonio Facciorusso (ORCID: https://orcid.org/0000-0002-2107-2156)
- Giovanni Marasco (ORCID: https://orcid.org/0000-0001-7167-8773)
- Rachele Del Sordo (ORCID: https://orcid.org/0000-0003-3930-2957)
- Marcello Fabio Maida (ORCID: https://orcid.org/0000-0002-4992-9289)
- Alessandro Vitello (ORCID: https://orcid.org/0000-0001-9099-9468)
- Marco Daperno (ORCID: https://orcid.org/0000-0002-0217-6603)
- Giulio Calabrese (ORCID: https://orcid.org/0000-0002-0802-3173)
- Giammarco Mocci (ORCID: https://orcid.org/0000-0002-9263-7409)
- Vincenzo Villanacci (ORCID: https://orcid.org/0000-0002-6774-1060)
- Sandro Sferrazza (ORCID: https://orcid.org/0000-0002-7595-0129)
- Caterina Fattorini
- Fabio Salvatore Macaluso (ORCID: https://orcid.org/0000-0001-5128-3846)
- Manuele Furnari (ORCID: https://orcid.org/0000-0001-6424-079X)
- Nicola Decarli
- Dario Ligresti (ORCID: https://orcid.org/0000-0002-4213-0482)
- Matteo Tacelli
- Giorgia Locci
- Lucrezia Laschi
Institutions
- University of Salento (IT)
- Vita-Salute San Raffaele University (IT)
- Università degli Studi di Enna Kore (IT)
- University of Perugia (IT)
- Ospedale Vincenzo Cervello (IT)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- Nuovo Ospedale San Giovanni di Dio (IT)
- Federico II University Hospital (IT)
- Azienda USL di Bologna (IT)
- A. O. Ordine Mauriziano di Torino (IT)
- Ospedale Misericordia - Grosseto (IT)
- Azienda di Rilievo Nazionale ed Alta Specializzazione (IT)
- Ospedale Policlinico San Martino (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Azienda Usl Toscana Centro (IT)
- Azienda Ospedaliera G. Brotzu (IT)
- Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (IT)
- University of Naples Federico II (IT)
- University of Brescia (IT)
- University of Genoa (IT)
- University of Bologna (IT)
Publication Details
- Journal
- United European Gastroenterology Journal
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1002/ueg2.70161
- Primary Topic
- Microscopic Colitis
- Type
- article
- Field-Weighted Citation Impact
- 0.00