Hypoxia, iron, and ferroptosis: a novel perspective on pheochromocytoma progression and therapy

Exploiting mutation-specific dysregulation of iron metabolism to trigger ferroptosis may provide a novel therapeutic strategy for therapy-resistant pheochromocytomas.

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Publication Details

Journal
European Journal of Endocrinology
Published
2025-11-26
DOI
https://doi.org/10.1093/ejendo/lvaf248
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Hypoxia, iron, and ferroptosis: a novel perspective on pheochromocytoma progression and therapy

Sawako Suzuki, Shinichi Sakamoto, Hisashi Koide, Tomohiko Ichikawa et al.
European Journal of Endocrinology
Ferroptosis and cancer prognosis
article

Hypoxia, iron, and ferroptosis: a novel perspective on pheochromocytoma progression and therapy

Sawako Suzuki, Shinichi Sakamoto, Hisashi Koide, Tomohiko Ichikawa, Kazuki Ishiwata, Yusuke Imamura, Katsushi Igarashi, Akiko Ishida, Suzuka Watanabe, Koutaro Yokote, Yoshihito Ozawa, Yutaro Ruike, Masafumi Sugo, Masanori Fujimoto, Kohei Takahashi, Rei Hashimoto, Kumiko Naito, Jun-ichiro Ikeda
article en

Abstract

Exploiting mutation-specific dysregulation of iron metabolism to trigger ferroptosis may provide a novel therapeutic strategy for therapy-resistant pheochromocytomas.

European Journal of EndocrinologyVol. 193(6)
Chiba University (JP), Chiba University Hospital (JP)
Openalex Percentile: Top 41%
Ferroptosis and cancer prognosis
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