Impact of multidomain lifestyle intervention on dynamics of cognitive frailty: post hoc analysis of the FINGER trial
The 2-year multidomain lifestyle intervention was effective in preventing and reversing CF. Participants with MCI or pre-frailty/frailty were both at increased risk for CF compared with healthy participants.
Authors
- Hanna-Maria Roitto
- Jenni Lehtisalo (ORCID: https://orcid.org/0000-0002-8818-0848)
- Tiia Ngandu (ORCID: https://orcid.org/0000-0002-3698-2021)
- Timo Strandberg (ORCID: https://orcid.org/0000-0001-6299-925X)
- Esko Levälahti
- Jenni Kulmala (ORCID: https://orcid.org/0000-0003-0194-5551)
- Jaakko Tuomilehto (ORCID: https://orcid.org/0000-0002-3424-0745)
- Miia Kivipelto (ORCID: https://orcid.org/0009-0001-1069-1787)
- Tiina Laatikainen
- Hilkka Soininen
- Riitta Antikainen
- Johanna Pöyhönen (ORCID: https://orcid.org/0009-0003-1524-6134)
Institutions
- University of Helsinki (FI)
- Tampere University (FI)
- University of Eastern Finland (FI)
- Oulu University Hospital (FI)
- Helsinki University Hospital (FI)
- Karolinska Institutet (SE)
- Karelia University of Applied Sciences (FI)
- Finnish Institute for Health and Welfare (FI)
- Escuela Nacional de Sanidad (ES)
- Kuopio University Hospital (FI)
- Tampere University (FI)
- MRC Unit for Lifelong Health and Ageing (GB)
- Imperial College London (GB)
- Oulu University of Applied Sciences (FI)
- University of Oulu (FI)
Publication Details
- Journal
- The Journals of Gerontology Series A
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1093/gerona/glaf275
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Foundation for Cardiovascular Research
- Yrjö Jahnssonin Säätiö
- EU Joint Programme – Neurodegenerative Disease Research
- Kela
- Suomen Kulttuurirahasto
- Hjärnfonden
- Juho Vainion Säätiö
- Karolinska Institutet
- Päivikki ja Sakari Sohlbergin Säätiö
- Vetenskapsrådet
- NordForsk
- Sydäntutkimussäätiö
- Sigrid Juséliuksen Säätiö
- Forskningsrådet om Hälsa, Arbetsliv och Välfärd
- Alzheimerfonden
- Center for Innovative Medicine