Transient Receptor Potential Channels as Key Regulators of Neuroinflammation in Neurological Disorders: Mechanistic Insights, Therapeutic Potentials, and Future Directions
By integrating mechanistic insights with translational perspectives, this review highlights TRP channels as promising targets for precision medicine and underscores their potential in the development of novel, mechanism-based therapies for complex neurological disorders, thereby advancing a new era of targeted neuroimmunomodulation.
Authors
- Lang Zeng (ORCID: https://orcid.org/0000-0003-3157-1087)
- Shiqing Zhang (ORCID: https://orcid.org/0000-0002-0785-5461)
- Yujun Feng (ORCID: https://orcid.org/0000-0001-5046-6085)
- Yinyin Chen (ORCID: https://orcid.org/0000-0002-1192-671X)
- Daji Guo (ORCID: https://orcid.org/0000-0002-6316-3443)
- Lei Shi (ORCID: https://orcid.org/0000-0002-0471-484X)
- Yubin Xian (ORCID: https://orcid.org/0000-0002-3906-0612)
- Meng Cai (ORCID: https://orcid.org/0000-0002-7122-4736)
- Chun Hu (ORCID: https://orcid.org/0000-0002-8898-4280)
Institutions
- Jinan University (CN)
- South China Normal University (CN)
- Guangdong Pharmaceutical University (CN)
- Ministry of Education (RW)
- Laboratoire de Chémo-biologie synthétique et thérapeutique (FR)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/cns.70700
- Citations
- 2
- Primary Topic
- Ion Channels and Receptors
- Type
- article
- Field-Weighted Citation Impact
- 2.93