Spontaneous pneumomediastinum: a rare cause of acute chest pain

A patient in late adolescence presented with sudden pleuritic chest pain at rest. Chest radiograph showed pneumomediastinum with associated subcutaneous emphysema. CT thorax with oral contrast confirmed spontaneous pneumomediastinum (SPM) and excluded oesophageal or tracheobronchial injury. SPM occurs when alveolar rupture allows air to track along perivascular sheaths into the mediastinum, known as the Macklin effect. The patient remained clinically stable during hospital observation and required only simple analgesia. A repeat chest radiograph showed no progression. The patient was discharged without complications. This case emphasises the need to consider pneumomediastinum in otherwise healthy individuals presenting with acute chest pain.

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Publication Details

Journal
BMJ Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1136/bcr-2025-270230
Primary Topic
Pneumothorax, Barotrauma, Emphysema
Type
article
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article

Spontaneous pneumomediastinum: a rare cause of acute chest pain

Mohammed I M Altelbani
BMJ Case Reports
Pneumothorax, Barotrauma, Emphysema
article

Spontaneous pneumomediastinum: a rare cause of acute chest pain

Mohammed I M Altelbani
article en

Abstract

A patient in late adolescence presented with sudden pleuritic chest pain at rest. Chest radiograph showed pneumomediastinum with associated subcutaneous emphysema. CT thorax with oral contrast confirmed spontaneous pneumomediastinum (SPM) and excluded oesophageal or tracheobronchial injury. SPM occurs when alveolar rupture allows air to track along perivascular sheaths into the mediastinum, known as the Macklin effect. The patient remained clinically stable during hospital observation and required only simple analgesia. A repeat chest radiograph showed no progression. The patient was discharged without complications. This case emphasises the need to consider pneumomediastinum in otherwise healthy individuals presenting with acute chest pain.

BMJ Case ReportsVol. 18(12)
NHS Greater Glasgow and Clyde (GB)
Openalex Percentile: Top 41%
Pneumothorax, Barotrauma, Emphysema
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