Fine-needle aspiration in infected necrotizing pancreatitis in the delayed intervention era: a <i>post hoc</i> analysis of safety, microbiological yield and therapeutic implications
This study suggests that diagnostic percutaneous FNA is a safe procedure with no observed complications, that may be useful in guiding antimicrobial therapy in patients with infected necrotizing pancreatitis, especially when delaying or omitting drainage procedures. Prospective studies and clinical trials are needed to confirm this. Percutaneous FNA is preferred over endoscopic FNA, as the latter carries a high risk of sample contamination.
Authors
- Rogier P. Voermans (ORCID: https://orcid.org/0000-0002-9969-019X)
- Hjalmar C. van Santvoort (ORCID: https://orcid.org/0009-0007-1218-2883)
- Wouter L. Curvers
- Marc G. Besselink (ORCID: https://orcid.org/0000-0003-2650-9350)
- Robert C. Verdonk (ORCID: https://orcid.org/0000-0001-5591-0499)
- Stefan A.W. Bouwense (ORCID: https://orcid.org/0000-0002-7600-9429)
- Peter van Duijvendijk (ORCID: https://orcid.org/0000-0002-0441-6180)
- Tom Seerden
- Marja A. Boermeester (ORCID: https://orcid.org/0000-0003-3890-8105)
- Adriaan C.I.T.L. Tan (ORCID: https://orcid.org/0000-0002-7389-5437)
- Fons F. van den Berg (ORCID: https://orcid.org/0000-0001-6494-4287)
- Elske Sieswerda (ORCID: https://orcid.org/0000-0001-5819-4918)
- Hester C. Timmerhuis (ORCID: https://orcid.org/0000-0001-5714-4951)
- Marco J. Bruno (ORCID: https://orcid.org/0000-0001-9181-5499)
- Lotte Boxhoorn (ORCID: https://orcid.org/0000-0001-7808-1734)
- Ben Witteman (ORCID: https://orcid.org/0000-0002-1341-8540)
- Rutger Quispel (ORCID: https://orcid.org/0000-0002-6109-9310)
- Niels G. Venneman (ORCID: https://orcid.org/0000-0002-9418-057X)
- Martijn W.J. Stommel (ORCID: https://orcid.org/0000-0002-4257-5254)
- Thomas L. Bollen (ORCID: https://orcid.org/0000-0002-5734-9823)
- Jan Willem Haveman (ORCID: https://orcid.org/0000-0002-5272-7565)
- Tessa E H Römkens (ORCID: https://orcid.org/0000-0002-4184-9823)
- Jeroen M. Jansen (ORCID: https://orcid.org/0000-0002-7639-9527)
- T. Schwartz (ORCID: https://orcid.org/0009-0009-1440-1722)
- Astrid Beij
- Muhammed Hadithi
- Wouter L. Hazen
- Marcel B W Spanier
- Hannah S Pauw (ORCID: https://orcid.org/0009-0003-2487-8192)
Institutions
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- University of Groningen (NL)
- Maastricht University Medical Centre (NL)
- Gelre Hospitals (NL)
- Catharina Ziekenhuis (NL)
- Medisch Spectrum Twente (NL)
- Erasmus MC (NL)
- Radboud University Medical Center (NL)
- University Medical Center Utrecht (NL)
- Maastricht University (NL)
- Netherlands Center for Occupational Diseases (NL)
- Reinier de Graaf Hospital (NL)
- St. Antonius Ziekenhuis (NL)
- OLVG (NL)
- Amphia Ziekenhuis (NL)
- Maasstad Ziekenhuis (NL)
- Canisius-Wilhelmina Ziekenhuis (NL)
- Ziekenhuis Gelderse Vallei (NL)
- European Society of Clinical Microbiology and Infectious Diseases (CH)
- Elisabeth-TweeSteden Ziekenhuis (NL)
- Amsterdam University Medical Centers (NL)
- Rijnstate Hospital (NL)
- Meander Medisch Centrum (NL)
- Jeroen Bosch Ziekenhuis (NL)
- Oklahoma State University Center for Health Sciences (US)
- University of Amsterdam (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-11-28
- DOI
- https://doi.org/10.1093/jac/dkaf455
- Citations
- 1
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.01