Infantile hemiparesis secondary to periventricular leukomalacia: clinical findings and multidisciplinary rehabilitation outcomes

A middle childhood child with infantile hemiparesis is the subject of this case study. He has left-sided weakness and delays in both gross and fine motor milestones, particularly in the upper limb. The child's delayed cry and need for NICU admission, despite a full term and vaginal delivery, suggested perinatal hypoxia. The results of the MRI showed slight right lateral ventricular asymmetry and periventricular leukomalacia, which are signs of hypoxic-ischaemic encephalopathy. Clinical assessment revealed isolated motor impairment, hypertonia and elevated deep tendon reflexes. The start of physiotherapy was delayed due to the delayed diagnosis at middle childhood and the lack of early intervention. This case demonstrates the complexity of infantile hemiparesis and the importance of neuroimaging, physiotherapy and early identification in enhancing results. Timely developmental monitoring and parental education are crucial, as early detection and organised rehabilitation can greatly improve motor function, lessen impairment and improve the child's quality of life.

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Publication Details

Journal
BMJ Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1136/bcr-2025-268850
Primary Topic
Neonatal and fetal brain pathology
Type
article
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article

Infantile hemiparesis secondary to periventricular leukomalacia: clinical findings and multidisciplinary rehabilitation outcomes

Sharath Hullumani, Sakshi Ravindra Borkute
BMJ Case Reports
Neonatal and fetal brain pathology
article

Infantile hemiparesis secondary to periventricular leukomalacia: clinical findings and multidisciplinary rehabilitation outcomes

Sharath Hullumani, Sakshi Ravindra Borkute
article en

Abstract

A middle childhood child with infantile hemiparesis is the subject of this case study. He has left-sided weakness and delays in both gross and fine motor milestones, particularly in the upper limb. The child's delayed cry and need for NICU admission, despite a full term and vaginal delivery, suggested perinatal hypoxia. The results of the MRI showed slight right lateral ventricular asymmetry and periventricular leukomalacia, which are signs of hypoxic-ischaemic encephalopathy. Clinical assessment revealed isolated motor impairment, hypertonia and elevated deep tendon reflexes. The start of physiotherapy was delayed due to the delayed diagnosis at middle childhood and the lack of early intervention. This case demonstrates the complexity of infantile hemiparesis and the importance of neuroimaging, physiotherapy and early identification in enhancing results. Timely developmental monitoring and parental education are crucial, as early detection and organised rehabilitation can greatly improve motor function, lessen impairment and improve the child's quality of life.

BMJ Case ReportsVol. 18(12)
Physiotherapy New Zealand (NZ), Datta Meghe Institute of Higher Education and Research (IN)
Openalex Percentile: Top 50%
Neonatal and fetal brain pathology
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