Using the Difference Between Estimated Glomerular Filtration Rate by Cystatin C and Creatinine to Improve Mortality Risk Prediction in Elderly Patients With CKD in the HUNT Study
Including eGFR_diff into the kidney failure risk and mortality risk equations significantly improved mortality risk prediction, but not kidney failure, in patients with CKD. Serum creatinine level is influenced by many non-GFR determinants, including sarcopenia, and the discrepancy of creatinine versus cystatin C could be helpful in predialytic decision-making.
Authors
- Stein Hallan (ORCID: https://orcid.org/0000-0002-9045-3569)
- Ronit Katz (ORCID: https://orcid.org/0000-0001-7723-7469)
- Onur Potok (ORCID: https://orcid.org/0009-0005-1141-6401)
- Knut Asbjørn Rise Langlo (ORCID: https://orcid.org/0000-0003-1653-3541)
- Nisha Bansal (ORCID: https://orcid.org/0000-0002-9583-8628)
Institutions
- University of Washington (US)
- Norwegian University of Science and Technology (NO)
- St Olav's University Hospital (NO)
Publication Details
- Journal
- Kidney Medicine
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.xkme.2025.101129
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00