Age-related epidemiology and outcomes of sepsis in Japanese critical care units: a nationwide administrative claims database study

Sepsis in Japanese critical care units demonstrated substantial age-related differences in epidemiology, treatment, resource utilization, and outcomes. The disproportionately high mortality and reduced treatment intensity among the oldest patients underscore the complex clinical and ethical considerations involved in managing sepsis in aging societies. These findings emphasize the urgent need to adapt sepsis care models and critical care resource planning for the rapidly aging population in Japan and similar nations.