Risk of serious infections in patients with inflammatory bowel disease treated with biologic and small molecule therapies: a nationwide cohort study
Patients with IBD were at an increased risk of infections, even among those naïve to IMM and advanced therapies. There was no significant difference in the risk of infections across advanced therapy exposures.
Authors
- Ola Olén (ORCID: https://orcid.org/0000-0002-5478-7019)
- Hans Strid (ORCID: https://orcid.org/0000-0003-4651-6769)
- Susanna Jäghult (ORCID: https://orcid.org/0000-0002-1815-963X)
- Jonas Halfvarson (ORCID: https://orcid.org/0000-0003-0122-7234)
- Karl Mårild (ORCID: https://orcid.org/0000-0003-2285-8713)
- Ulrika L. Fagerberg (ORCID: https://orcid.org/0000-0003-2727-7280)
- Pär Myrelid (ORCID: https://orcid.org/0000-0001-7518-9213)
- Marie Andersson (ORCID: https://orcid.org/0000-0003-0607-9197)
- Martin Rejler (ORCID: https://orcid.org/0000-0003-3286-2898)
- Charlotte Hedin (ORCID: https://orcid.org/0000-0002-4921-8516)
- Jonas Filip Ludvigsson (ORCID: https://orcid.org/0000-0003-1024-5602)
- Pontus Nauclér (ORCID: https://orcid.org/0000-0002-8185-2648)
- Henrik Hjortswang
- Caroline A.M. Nordenvall (ORCID: https://orcid.org/0000-0002-5112-8894)
- Jordan E. Axelrad (ORCID: https://orcid.org/0000-0003-1951-7790)
- Jóhann P. Hreinsson (ORCID: https://orcid.org/0000-0002-0078-3063)
- Anders Forss (ORCID: https://orcid.org/0000-0002-1906-4982)
- Jonas Söderling (ORCID: https://orcid.org/0000-0001-9006-2835)
- Olof Grip (ORCID: https://orcid.org/0000-0001-5033-7451)
Institutions
- National Academy of Medicine (US)
- Karolinska University Hospital (SE)
- Örebro University (SE)
- Sahlgrenska University Hospital (SE)
- Karolinska Institutet (SE)
- Drottning Silvias barn- och ungdomssjukhus (SE)
- Sachs' Children and Youth Hospital (SE)
- Örebro University Hospital (SE)
- New York University (US)
- Columbia University (US)
- University of Gothenburg (SE)
Publication Details
- Journal
- Journal of Crohn s and Colitis
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1093/ecco-jcc/jjaf229
- Citations
- 1
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.82