Role of LINC00332 in colorectal cancer progression and paclitaxel resistance
LINC00332 promotes PTX resistance and EMT in CRC via WNT and NOTCH pathways activation. It can also be suggested as a potential diagnostic marker in early-stage CRC patients. Targeting LINC00332 may enhance PTX response, warranting further studies for therapeutic application.
Authors
- Negin Taghehchian
- Meysam Moghbeli (ORCID: https://orcid.org/0000-0001-9680-0309)
- Mahsa Palizkaran Yazdi
- Mohammad Reza Abbaszadegan
Institutions
- Mashhad University of Medical Sciences (IR)
Publication Details
- Journal
- Cell Division
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1186/s13008-025-00176-8
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00