Exosome and BCR-ABL mediated molecular alterations in endothelial cells in chronic myeloid leukemia: identification of seven genes and their regulatory network
This study identifies seven novel candidate biomarkers dysregulated in endothelial cells under combined BCR-ABL and exosomal stimulation, shedding light on the molecular crosstalk between leukemic cells and the vascular niche.
Authors
- Ming He (ORCID: https://orcid.org/0000-0001-9559-0733)
- Ni Luo (ORCID: https://orcid.org/0000-0002-4999-9770)
- H. F. Li
- Asad Zia (ORCID: https://orcid.org/0000-0002-3212-9170)
- Lei Feng (ORCID: https://orcid.org/0000-0002-3981-7646)
- Liying Song (ORCID: https://orcid.org/0009-0009-6100-4789)
- Kunmei Liu (ORCID: https://orcid.org/0000-0002-1018-3336)
- Zhenglei Shen
- Yasar Mehmood Yousafzai (ORCID: https://orcid.org/0000-0002-3479-6153)
- Xuezhong Gu (ORCID: https://orcid.org/0000-0001-6485-4919)
- Shiwen Zhang (ORCID: https://orcid.org/0000-0001-6892-2333)
- Yeying Zhou
- Wenwen Mao (ORCID: https://orcid.org/0000-0002-5297-2122)
- H.H. Le
- Jingying Zhu
- Yongjun Mao
- Honghua Cao
Institutions
- Khyber Medical College (PK)
- Kunming University (CN)
- Khyber Medical University (PK)
- Kunming Medical University (CN)
- First People's Hospital of Yunnan Province (CN)
- Longgang Central Hospital (CN)
- ShenZhen People’s Hospital (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-12-17
- DOI
- https://doi.org/10.7717/peerj.20371
- Primary Topic
- Chronic Myeloid Leukemia Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00