Claudin and Rab proteins are key molecular components involved in coccidiosis resistance in Portuguese Merino sheep

Given the role that Rab and Claudins play in host-parasite relationships, these results suggest the existence of reliable markers associated with resistance to coccidiosis. These markers should be explored in future studies to further validate their use in marker assisted selection, with the goal of enhancing sustainability of the breed conservation-management program.

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Publication Details

Journal
Genetics Selection Evolution
Published
2025-12-17
DOI
https://doi.org/10.1186/s12711-025-01020-x
Primary Topic
Coccidia and coccidiosis research
Type
article
Field-Weighted Citation Impact
0.00
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article

Claudin and Rab proteins are key molecular components involved in coccidiosis resistance in Portuguese Merino sheep

Luís Madeira de Carvalho, Cristina Martins, Pedro Vieira, Helga Waap et al.
Genetics Selection Evolution
Coccidia and coccidiosis research
article

Claudin and Rab proteins are key molecular components involved in coccidiosis resistance in Portuguese Merino sheep

Luís Madeira de Carvalho, Cristina Martins, Pedro Vieira, Helga Waap, Andreia J. Amaral, Tiago Perloiro, Natalia Campbell, Endika Varela-Martínez, L.T. Gama, RAISSA MARQUES DA SILVA, Fábio G. Teixeira, Ana Cristina Ferreira, Telmo Nunes, Ana Cristina Afonso, Dimitra Mainou, Inês Sarraguça
article en

Abstract

Given the role that Rab and Claudins play in host-parasite relationships, these results suggest the existence of reliable markers associated with resistance to coccidiosis. These markers should be explored in future studies to further validate their use in marker assisted selection, with the goal of enhancing sustainability of the breed conservation-management program.

Genetics Selection EvolutionVol. 58(1)
University of Lisbon (PT), University of the Basque Country (ES), Aristotle University of Thessaloniki (GR), University of Évora (PT), Sustainability Institute (ZA), Instituto de Medicina Tropical (PY), Instituto Nacional de Investigação Agrária e Veterinária (PT), Instituto Politécnico de Santarém (PT), Centre for Research in Anthropology (PT), Universidade Metropolitana de Santos (BR), Instituto Piaget (PT), Universidade Lusófona (PT)
Openalex Percentile: Top 54%
Coccidia and coccidiosis research
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