Nano-elemental imaging reveals zinc and calcium redistribution in human sperm during capacitation and hyperactivation

A deeper understanding of male fertility may be achieved by elucidating the multifaceted role of zinc in sperm function, particularly its interaction with calcium signaling pathways. By considering both the biochemical and ionic mechanisms alongside the physical aspects of sperm activity, a more precise assessment of sperm functionality becomes possible.

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Publication Details

Journal
F&S Science
Published
2025-12-01
DOI
https://doi.org/10.1016/j.xfss.2025.12.007
Primary Topic
Trace Elements in Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Nano-elemental imaging reveals zinc and calcium redistribution in human sperm during capacitation and hyperactivation

Simone Sala, Lorella Pascolo, Giuseppe Ricci, Elena Giolo et al.
F&S Science
Trace Elements in Health
article

Nano-elemental imaging reveals zinc and calcium redistribution in human sperm during capacitation and hyperactivation

Simone Sala, Lorella Pascolo, Giuseppe Ricci, Elena Giolo, Luisa Zupin, Maik Kahnt, Alessandra Gianoncelli, Stefania Luppi, Cristina Tufoni
article en

Abstract

A deeper understanding of male fertility may be achieved by elucidating the multifaceted role of zinc in sperm function, particularly its interaction with calcium signaling pathways. By considering both the biochemical and ionic mechanisms alongside the physical aspects of sperm activity, a more precise assessment of sperm functionality becomes possible.

F&S Science
Lund University (SE), IRCCS Materno Infantile Burlo Garofolo (IT), RISE Research Institutes of Sweden (SE), Elettra-Sincrotrone Trieste S.C.p.A. (IT), MAX IV Laboratory (SE)
Openalex Percentile: Top 52%
Trace Elements in Health
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