Sex chromosome dosage compensation in a sex reversing skink is not influenced by sexual phenotype
Partial dosage compensation in the Eastern three-lined skink is similar to several other species of lizard. However, here for the first time we describe dosage compensation in a lizard with natural sex reversal, and show that in sex reversed individuals dosage compensation of the X chromosome follows genotypic sex and not phenotypic sex.
Authors
- Jillian M. Hammond (ORCID: https://orcid.org/0000-0002-4045-4571)
- Hardip R. Patel (ORCID: https://orcid.org/0000-0003-3169-049X)
- Arthur Georges (ORCID: https://orcid.org/0000-0003-2428-0361)
- Aurora Ruiz‐Herrera (ORCID: https://orcid.org/0000-0003-3868-6151)
- Jiang Chang (ORCID: https://orcid.org/0000-0001-7064-9321)
- Jennifer A. Marshall Graves (ORCID: https://orcid.org/0000-0001-6480-7856)
- Ashley M. Milton (ORCID: https://orcid.org/0000-0002-2847-2777)
- Benjamin J. Hanrahan (ORCID: https://orcid.org/0000-0001-9567-0071)
- Duminda S. B. Dissanayake (ORCID: https://orcid.org/0000-0002-7307-4639)
- Ira W. Deveson (ORCID: https://orcid.org/0000-0003-3861-0472)
- Nicholas C. Lister (ORCID: https://orcid.org/0000-0002-6597-4784)
- Paul D. Waters (ORCID: https://orcid.org/0000-0002-4689-8747)
- Andre L. M. Reis
Institutions
- Australian National University (AU)
- Universitat Autònoma de Barcelona (ES)
- Garvan Institute of Medical Research (AU)
- University of Canberra (AU)
- La Trobe University (AU)
- UNSW Sydney (AU)
- Institut Català de Paleontologia Miquel Crusafont (ES)
- Murdoch Children's Research Institute (AU)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1186/s12864-025-12217-1
- Primary Topic
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 0.00