Failure of pharmacological DVT prophylaxis due to cold chain disruption: a six-month audit from a tertiary surgical ward in Cairo

Cold chain failure was strongly associated with prophylaxis failure and is the most plausible contributor, though definitive pharmacological degradation was not confirmed. Infrastructure monitoring and mechanical prophylaxis adherence are essential to effective thromboprophylaxis. A prospective re-audit is scheduled following corrective measures.

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Publication Details

Journal
BMC Surgery
Published
2025-12-17
DOI
https://doi.org/10.1186/s12893-025-03326-5
Primary Topic
Infection Control in Healthcare
Type
article
Field-Weighted Citation Impact
0.00
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article

Failure of pharmacological DVT prophylaxis due to cold chain disruption: a six-month audit from a tertiary surgical ward in Cairo

Abdelrahman Lotfy, Ahmed Ismail Ahmed Shafik, Haytham Elessawy, Youssef Karkoucha Gobrial
BMC Surgery
Infection Control in Healthcare
article

Failure of pharmacological DVT prophylaxis due to cold chain disruption: a six-month audit from a tertiary surgical ward in Cairo

Abdelrahman Lotfy, Ahmed Ismail Ahmed Shafik, Haytham Elessawy, Youssef Karkoucha Gobrial
article en

Abstract

Cold chain failure was strongly associated with prophylaxis failure and is the most plausible contributor, though definitive pharmacological degradation was not confirmed. Infrastructure monitoring and mechanical prophylaxis adherence are essential to effective thromboprophylaxis. A prospective re-audit is scheduled following corrective measures.

BMC SurgeryVol. 26(1)
Cairo University (EG)
Openalex Percentile: Top 53%
Infection Control in Healthcare
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