Downregulation of lncRNA HOTTIP alleviates neuropathic pain and inflammation in chronic constriction injury rats by targeting miR-216a-5p
HOTTIP contributes to the worsening of NP and neuroinflammation by modulating the miR-216a-5p/JAK2 pathway, exerting analgesic protective effects, indicating its potential as a therapeutic target for NP.
Authors
- A Runa (ORCID: https://orcid.org/0009-0000-2928-3102)
- Ren-Na Wu (ORCID: https://orcid.org/0009-0000-4169-1766)
- Lengge Si (ORCID: https://orcid.org/0009-0002-1746-5018)
- Gen Zan (ORCID: https://orcid.org/0009-0000-5513-1022)
- Yasula Ba (ORCID: https://orcid.org/0009-0002-5418-5349)
- Gerile Sude (ORCID: https://orcid.org/0009-0002-3859-1363)
Institutions
- Inner Mongolia Medical University (CN)
Publication Details
- Journal
- The Korean journal of pain
- Published
- 2025-12-17
- DOI
- https://doi.org/10.3344/kjp.25241
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Inner Mongolia Medical University