Rare case of skull metastasis from endometrial carcinoma sparing lymph nodes: a case report

Endometrial cancer is common especially among females. It could disseminate through direct, lymphatic, and hematogenous spread. On the other hand, cutaneous metastases are extremely rare. We reported a case of a 70-year-old female with a history of early-stage endometrial carcinoma (Stage IB, Grade 2) who developed a rare skull metastasis sparing lymph nodes. Given the patient's poor performance status and comorbidities, she was deemed unfit for systemic chemotherapy. Palliative care was initiated, focusing on symptom management. This case underscores the importance of considering atypical metastatic presentations in endometrial cancer and highlights the challenges in diagnosis and management.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-11-26
DOI
https://doi.org/10.1093/jscr/rjaf987
Primary Topic
Brain Metastases and Treatment
Type
article
Field-Weighted Citation Impact
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article

Rare case of skull metastasis from endometrial carcinoma sparing lymph nodes: a case report

Dania Al-Nuaimi, Turki M. Almuhaimid, Abdulrahman Subaih, Danah Aldulaijan
Journal of Surgical Case Reports
Brain Metastases and Treatment
article

Rare case of skull metastasis from endometrial carcinoma sparing lymph nodes: a case report

Dania Al-Nuaimi, Turki M. Almuhaimid, Abdulrahman Subaih, Danah Aldulaijan
article en

Abstract

Endometrial cancer is common especially among females. It could disseminate through direct, lymphatic, and hematogenous spread. On the other hand, cutaneous metastases are extremely rare. We reported a case of a 70-year-old female with a history of early-stage endometrial carcinoma (Stage IB, Grade 2) who developed a rare skull metastasis sparing lymph nodes. Given the patient's poor performance status and comorbidities, she was deemed unfit for systemic chemotherapy. Palliative care was initiated, focusing on symptom management. This case underscores the importance of considering atypical metastatic presentations in endometrial cancer and highlights the challenges in diagnosis and management.

Journal of Surgical Case ReportsVol. 2025(12)
Royal Commission for Jubail and Yanbu (SA), King Fahad Specialist Hospital (SA), Imam Abdulrahman Al Faisal Hospital (SA), Imam Abdulrahman Bin Faisal University (SA)
Openalex Percentile: Top 41%
Brain Metastases and Treatment
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Rare case of skull metastasis from endometrial carcinoma sparing lymph nodes: a case report — Dania Al-Nuaimi, Turki M. Almuhaimid, et al. · Journal of Surgical Case Reports (2025) | TGRS Research Map | TGRS