Eosinophilic Esophagitis: real-life outcomes over 10 years in a Canadian pediatric centre

This Canadian study reveals remission rates lower than short term studies, but a reduction in strictures in follow-up. Real-life challenges, such as not returning for follow up endoscopy (∼20%), despite no direct care costs, challenges with adherence with ∼20% not taking any therapy and over half not taking medications as prescribed contribute towards remission rates below 50% regardless of treatment. Better patient engagement, addressing barriers to treatment and follow up and exploring novel therapies are needed.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2025-12-17
DOI
https://doi.org/10.3389/fped.2025.1687724
Primary Topic
Eosinophilic Esophagitis
Type
article
Field-Weighted Citation Impact
0.00
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article

Eosinophilic Esophagitis: real-life outcomes over 10 years in a Canadian pediatric centre

Edmond S. Chan, Stephanie C. Erdle, Jonathan W. Bush, Nikola Deretic et al.
Frontiers in Pediatrics
Eosinophilic Esophagitis
article

Eosinophilic Esophagitis: real-life outcomes over 10 years in a Canadian pediatric centre

Edmond S. Chan, Stephanie C. Erdle, Jonathan W. Bush, Nikola Deretic, Vishal Avinashi
article en

Abstract

This Canadian study reveals remission rates lower than short term studies, but a reduction in strictures in follow-up. Real-life challenges, such as not returning for follow up endoscopy (∼20%), despite no direct care costs, challenges with adherence with ∼20% not taking any therapy and over half not taking medications as prescribed contribute towards remission rates below 50% regardless of treatment. Better patient engagement, addressing barriers to treatment and follow up and exploring novel therapies are needed.

Frontiers in PediatricsVol. 13
BC Children's Hospital (CA)
Openalex Percentile: Top 40%
Eosinophilic Esophagitis
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