In the era of copy number variation sequencing: changes in the target population for prenatal diagnosis and what is the optimal prenatal diagnostic strategy?
In the era of CNV-Seq, the target population for prenatal diagnosis is expanding. Combining CNV-Seq with karyotyping can increase the DRs of fetal chromosomal abnormalities. Therefore, combined testing is an efficient and relatively cost-effective prenatal diagnostic strategy.
Authors
- Shuwen Xin
- Rongxiang Li
- Sheng Teng (ORCID: https://orcid.org/0000-0002-5386-6217)
- Shaozhe Yang (ORCID: https://orcid.org/0009-0009-7306-827X)
- Yanqi He (ORCID: https://orcid.org/0000-0001-9548-6506)
- Yanlin Gao (ORCID: https://orcid.org/0009-0003-5477-6402)
- Xiuhong Fu (ORCID: https://orcid.org/0009-0004-4326-6113)
Institutions
- Luohe Medical College (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-12-17
- DOI
- https://doi.org/10.3389/fmed.2025.1610477
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00