The impact of diabetes mellitus on biomarkers for the diagnosis of periprosthetic joint infection
Diabetes does not affect the biomarker levels in patients with PJI. However, for diabetic patients, the diagnostic thresholds of CRP and ESR are relatively higher. Thus, caution should be exercised in clinical diagnosis to avoid false positives. Among all indicators, the CAR demonstrates the best diagnostic efficacy and can serve as the preferred biomarker for PJI patients with comorbid diabetes.
Authors
- Zheng Dong (ORCID: https://orcid.org/0000-0003-3538-8095)
- Xi Chen (ORCID: https://orcid.org/0000-0003-0165-6426)
- Jing Chen (ORCID: https://orcid.org/0000-0002-2681-0349)
- Hairong Ding
- Ting-Yu Cheng (ORCID: https://orcid.org/0000-0003-2632-4073)
- Jun Qiu (ORCID: https://orcid.org/0000-0002-4822-7736)
- Changfa Qu (ORCID: https://orcid.org/0000-0003-1706-0336)
Institutions
- Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.3389/fcimb.2025.1720431
- Citations
- 1
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.01