Bioinformatic and experimental identification and characterization of Clostridioides difficile lipoproteins as potential vaccine candidates
These results indicate that both lipoproteins play a significant role in <i>C. difficile</i> adhesion and that LP1 and LP2 are promising immunogens for preventing <i>C. difficile</i> colonization.
Authors
- Lubem Nathanel Agbendeh
- Soumyadeep Chakraborty (ORCID: https://orcid.org/0000-0002-3882-7172)
- Angshumoy Roy (ORCID: https://orcid.org/0000-0001-7248-8576)
- Junling Qin
- Αναστασία Τοματσίδου
- Joshua Heuler
- Hyeun Bum Kim (ORCID: https://orcid.org/0000-0003-1366-6090)
- Shaohui Wang (ORCID: https://orcid.org/0000-0002-4735-1225)
- Xingmin Sun
Institutions
- University of South Florida (US)
- Virginia Tech (US)
- Dankook University (KR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.3389/fimmu.2025.1650364
- Primary Topic
- Clostridium difficile and Clostridium perfringens research
- Type
- article
- Field-Weighted Citation Impact
- 0.00