A retrospective study on pediatric pertussis: comprehensive evaluation of symptoms, laboratory indicators, and diagnostic efficacy of case definitions
The age distribution of pediatric pertussis shifted from young infants to preschool- and school-aged children. Clinical features alone are insufficient for reliable diagnosis due to overlap with non-pertussis cases. Elevated neutrophil count serves as an independent predictor of ICU admission, highlighting its potential utility for early risk stratification in pediatric pertussis.
Authors
- Mingyong Luo (ORCID: https://orcid.org/0000-0002-1202-1429)
- Weixiang Wu
- Jun Xiong (ORCID: https://orcid.org/0000-0003-0062-9784)
- Minling Zheng
- Qiongdan Mai (ORCID: https://orcid.org/0000-0002-7166-095X)
- Yasha Luo (ORCID: https://orcid.org/0000-0002-2690-0221)
- Yanting Qin
- Junfei Guo (ORCID: https://orcid.org/0000-0001-7903-8252)
- Weiming Lai
Institutions
- Southern University of Science and Technology (CN)
- Shenzhen Maternity and Child Healthcare Hospital (CN)
- Guangdong Province Women and Children Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.3389/fcimb.2025.1694670
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Traditional Chinese Medicine Bureau of Guangdong Province