Emergence of KPC-2 and NDM-13-coproducing carbapenem-resistant hypervirulent Klebsiella pneumoniae with high-risk sequence type ST11
This study reports a clinical ST11-K64 CR-hvKP strain co-producing KPC-2 and NDM-13, which carried multiple resistance genes on two resistant plasmids, along with virulence factors enhancing its pathogenicity. These findings underscore the imperative for enhanced surveillance to mitigate the dissemination of such high-risk, multidrug-resistant, and hypervirulent strains.
Authors
- Jill Jin
- Liru Wang (ORCID: https://orcid.org/0009-0007-3465-3279)
- Gang Li (ORCID: https://orcid.org/0000-0001-6778-2842)
- Na Yang (ORCID: https://orcid.org/0000-0002-4561-1249)
- T. F. Lai
- Jia Tao
- Xinxin Hu (ORCID: https://orcid.org/0009-0004-6427-020X)
- Hui Fu
Institutions
- Ningxia Medical University (CN)
- Ningxia Medical University General Hospital (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.3389/fmicb.2025.1683102
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00