Glucose-6-phosphate dehydrogenase deficiency facilitates hepatitis E virus entry and aggravates liver injury

Patients with G6PDd are susceptible to HEV infection. The facilitation of HEV entry and aggravation of oxidative stress may contribute to HEV susceptibility in patients with G6PDd and severe disease.

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Publication Details

Journal
Virology Journal
Published
2025-12-17
DOI
https://doi.org/10.1186/s12985-025-03031-y
Primary Topic
Hepatitis Viruses Studies and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Glucose-6-phosphate dehydrogenase deficiency facilitates hepatitis E virus entry and aggravates liver injury

Jiankun Liu, Xiaoxia Hu, Dongxue Chen, Fanlin Xia et al.
Virology Journal
Hepatitis Viruses Studies and Epidemiology
article

Glucose-6-phosphate dehydrogenase deficiency facilitates hepatitis E virus entry and aggravates liver injury

Jiankun Liu, Xiaoxia Hu, Dongxue Chen, Fanlin Xia, Fen Huang, Yun Xue, Yi Liu
article en

Abstract

Patients with G6PDd are susceptible to HEV infection. The facilitation of HEV entry and aggravation of oxidative stress may contribute to HEV susceptibility in patients with G6PDd and severe disease.

Virology JournalVol. 23(1)
Kunming University of Science and Technology (CN), Kunming Medical University (CN), People's Liberation Army 401 Hospital (CN), 81th Hospital of PLA (CN), Yunnan Provincial Department of Education (CN)
Openalex Percentile: Top 46%
Hepatitis Viruses Studies and Epidemiology
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