Female hormone therapy and risk of intracranial hemorrhage and focal neurological deficits in patients with cavernous malformations of the central nervous system
The study shows that female patients with a diagnosis of cerebral cavernous malformation receiving female hormone therapy do not experience a significant higher likelihood of intracranial hemorrhage or focal neurological deficit. These findings indicate that, despite the observed tendency, female hormone therapy does not significantly alter the risk of these events in the observed female patients.
Authors
- Victor E. Staartjes (ORCID: https://orcid.org/0000-0003-1039-2098)
- Selina Nager
- Sena Özkaratufan
- Oliver Bozinov (ORCID: https://orcid.org/0000-0002-4620-3992)
- Julia Velz (ORCID: https://orcid.org/0000-0001-8027-9918)
- Luca Regli (ORCID: https://orcid.org/0000-0003-4639-4474)
- Saskia Wildi
- Vittorio Stumpo (ORCID: https://orcid.org/0000-0002-8175-0035)
- Niklaus Krayenbühl (ORCID: https://orcid.org/0000-0003-1089-221X)
Institutions
- University of Zurich (CH)
- University of St.Gallen (CH)
- Kantonsspital St. Gallen (CH)
- University Hospital of Zurich (CH)
- University Children's Hospital Zurich (CH)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.3389/fneur.2025.1658980
- Primary Topic
- Vascular Malformations Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00