Asparagine-related biomarkers and regulatory mechanisms in type 2 diabetes mellitus
This study identified PPP1CA and CTSD as asparagine-related biomarkers driving immune-metabolic crosstalk in T2DM. The príicted regulatory networks and therapeutic compounds provided novel insights into T2DM mechanisms and potential intervention strategies.
Authors
- Bo Cao (ORCID: https://orcid.org/0000-0002-1626-7274)
- Peiyin Chen (ORCID: https://orcid.org/0000-0001-8636-526X)
- Tao Cai (ORCID: https://orcid.org/0000-0002-2877-8637)
- Lu Gan (ORCID: https://orcid.org/0000-0002-4862-3747)
- Jiayi Xia
- Marie‐France Kong
Institutions
- People's Liberation Army 401 Hospital (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- Guizhou Provincial People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-12-17
- DOI
- https://doi.org/10.3389/fmolb.2025.1733878
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00