Despite increasing use of integrase inhibitors to treat HIV infection, resistance to this class remains stable

Although the use of INSTIs has increased over time with differences in the duration of use, we did not observe a corresponding increase in the proportion of ARV-treated PLWHIV who experienced virological failure with INSTI-resistant viruses during the study period.

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Publication Details

Journal
Journal of Antimicrobial Chemotherapy
Published
2025-12-04
DOI
https://doi.org/10.1093/jac/dkaf454
Primary Topic
HIV/AIDS drug development and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Despite increasing use of integrase inhibitors to treat HIV infection, resistance to this class remains stable

Basma Abdi, Elisa Teyssou, Antoine Fayçal, Christine Katlama et al.
Journal of Antimicrobial Chemotherapy
HIV/AIDS drug development and treatment
article

Despite increasing use of integrase inhibitors to treat HIV infection, resistance to this class remains stable

Basma Abdi, Elisa Teyssou, Antoine Fayçal, Christine Katlama, Vincent Cálvez, Romain Palich, Anne‐Geneviève Marcelin, Marc Wirden, Marc‐Antoine Valantin, Valérie Pourcher, Sophie Sayon, Antoine Fauchois, Roland Tubiana, Luminita Schneider, Rachid Agher, Cathia Soulié
article en

Abstract

Although the use of INSTIs has increased over time with differences in the duration of use, we did not observe a corresponding increase in the proportion of ARV-treated PLWHIV who experienced virological failure with INSTI-resistant viruses during the study period.

Journal of Antimicrobial ChemotherapyVol. 81(1)
Inserm (FR), Sorbonne Université (FR), Assistance Publique – Hôpitaux de Paris (FR), Institut Pierre Louis d‘Épidémiologie et de Santé Publique (FR)
Openalex Percentile: Top 53%
HIV/AIDS drug development and treatment
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Despite increasing use of integrase inhibitors to treat HIV infection, resistance to this class remains stable — Basma Abdi, Elisa Teyssou, et al. · Journal of Antimicrobial Chemotherapy (2025) | TGRS Research Map | TGRS