Swimming exercise improves vascular function and mitigates cardiac apoptotic response via Bcl-2 and Caspase-3 pathway in streptozotocin-induced diabetic rats: in vivo and in silico molecular docking study
Swimming exercise mitigates the adverse effects of STZ-DM, probably by improving endothelial functions and reducing cell damage via the Bcl-2 and caspase-3 pathway.
Authors
- Daniel Udofia Owu (ORCID: https://orcid.org/0000-0002-8264-9131)
- Ogechukwu Grace Onuoha
- Idara Asuquo Okon (ORCID: https://orcid.org/0000-0003-3256-5404)
- J. E. Amadi
- Nelson N. Orie (ORCID: https://orcid.org/0000-0002-4277-3779)
- Victor Otu Oka (ORCID: https://orcid.org/0000-0001-7230-6293)
- Nioking Amadi (ORCID: https://orcid.org/0000-0002-1200-0492)
- Erdi Can Aytar (ORCID: https://orcid.org/0000-0001-6045-0183)
- Gabriel Otu Ujong (ORCID: https://orcid.org/0000-0002-1015-5810)
- Athira Jacob (ORCID: https://orcid.org/0000-0002-5948-3655)
- Favor Akpakpan Udoeyop
- E Bassey (ORCID: https://orcid.org/0009-0002-8974-5932)
- Bubaraye Robson Uko
- David Chukwunyerem Nwachukwu
Institutions
- University of Port Harcourt (NG)
- Usak University (TR)
- Catholic University of Health and Allied Sciences (TZ)
- Kampala International University (UG)
- Godfrey Okoye University (NG)
- University of Cross River State (NG)
- University of Calabar (NG)
- PAMO University of Medical Sciences
- University College London (GB)
- Rivers State University (NG)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1186/s40001-025-03671-4
- Primary Topic
- Cardiac Ischemia and Reperfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00